Hello Friends according to Internationalcannabinoid Research Society(ICRS) ,Association of Cannabis Specialists & Society of Cannabis Clinicians- CBD has many health benefits and it have wonderful clinical effects in small as well as large Animals without any side effect in chronic clinical cases it works effectively. Today will brief on CBD in pets.
CBD IN PETS:-
CBD products for pets have become very popular and many producers of products for humans have started similar lines marketed for our pets.
All mammals have an ENDOCANNABINOID SYSTEM there are CB1 & CB2 receptors throughout the bodies of your dogs and cats ,ready to make use of the therapeutic benefits of CBD.
Pets are much smaller doses than an adult human and require much smaller doses than humans do.
Many people are looking to cannabis, whether its medical marijuana, or medical hemp to help their pets when conventional medications aren’t working or are ridiculously expensive. Many times pet parents find, much to their amazement, that a little bit of cannabis goes a long way to help their pet’s conditions.
But, what many pet parents don’t know is that if your cannabis contains much THC, it may cause an adverse reaction in your dog, that causes them to lose their balance, and often times they will fall over uncontrollably. This condition in dogs is called “Static Ataxia” and is because, in the dog, as compared to the cat or the human or the horse, there are an abundance of THC receptors in the part of the dog brain that control coordination and balance. This part of the brain is called the “cerebellum”.
If you can start your dog out with a tiny dose of THC that isn’t high enough to be psychotropic, and give that every day for a week, your dog will develop tolerance to these adverse effects, and then you can gradually increase the amount of THC you are giving to produce the medical benefit you are looking for in your use of cannabis.
This is true for medical marijuana, that typically contains 5-35% THC, but is not true for medical hemp that by law only contains no more than 0.3% THC, and thus is not psychotropic, which means that it won’t interfere with your dog’s coordination. For many issues that dogs have, medical hemp is more than adequate to address those disease issues without worrying about your dog falling over or freaking out.
If you are lucky enough to live in a state with legal medical or recreational marijuana, you should see if you can find a product that tells you on the label what its potency is in terms of the numbers of milligrams of THC and CBD. Be sure to read the label carefully, as sometimes the amount expressed is for the entire bottle, so then you need to divide by the number of milliliters to get the amount of milligrams per milliliter or milligrams per biscuit or soft-chew. Once We know this amount, we can then pretty accurately give our dog a dosage that will help, and won’t hurt.
For products that state the amount of THC on the label, its important to start dosing based on the THC content, that way we are most likely to avoid side-effects have found that using a very low dose of THC of 0.11mg/kgbwt of pet’s body weight twice daily is a safe place to start. After you have given that dose, wait two hours for full effect. If dog seems a little glassy-eyed and out of it, or just stands there salivating and swaying back and forth with its hind legs held wide, then that dose is still too high for your dog. But if there are none of these symptoms, then you have found a good starting dose, and you should give that twice daily for a week before increasing the dosage to a higher dose for a better effect.
If you are using a hemp product, they usually tell you exactly how much hemp is in the bottle, and how much is in each milliliter.we have established a range of doses for hemp based cannabinoids such as CBD. This range starts at 0.11 mg/kg twice daily. The high end is 5 times that, or 0.55 mg/kg twice daily. usually start the patients on the low end of the dose, and give it for a week to observe for beneficial effects. Many times that low a dose will work well, and until it stops working well, stay at that dose. Increase it to 0.28 mg per pound twice daily as my next dosage tier, and keep it at that level until it starts to lose it effect. It may always be good at any of these dosages, and not necessarily need to be changed once you’ve seen benefit.
In my next post I will talk about the use of “Ratio Products” where you give a specific ratio between THC:CBD for specific conditions. Stay tuned, and if you have questions, enter them below in the comments section, that way I will answer them in the blog, and other people can benefit from our dialog
Dr. Rob Silver,
Licensed & renowned holistic Vet,
Cannabis practitioner ,Colorado
Delivery Methods(The variety of ways you can consume CBD are reffered as Delivery methods) Of CBD
Onset- 2 to 15 mins
Duration-2 to 4hrs
Options- Edibles, CBD oil,capsules
Onset- 30 to 90 mins
Duration- 6 to 8 hrs
Bioavailability- 6 to 15%
Options- Tinctures,strips,tablets,sprays, high potency oils
Onset- 15 to 30mins
Duration- 2 to 4 hrs
Bioavailability-6 to 20%
Onset- 15 to 30 mins
Duration- 2 to 4 hrs
onset- 15 to 20 mins
Duration- 4 to 8 hrs
Dosing Strategies: Figuring out the right individual dose of CBD or any cannabis medicine will be a process one you need to be actively engaged in and monitor closely to make the most out of these therapeutic compounds here are some strategies,tips, and tools to help you do just that
Start Low & Go Slow : This is tried and tested
Start low means, not surprisingly, start with a low dose. If pet is taking a CBD-dominant product (like a hemp-derived product with negligible THC or a cannabis product with a ratio of 20:1 or higher), this could be as little as 10 milligrams per day to start. If we are using a cannabis-based product with THC and individual may be a new cannabis consumer, so better to start with a very low dose of THC (1 to 2.5 milligrams), as pets sensitivity might be quite high.
CBD & MAJOR HEALTH CONDITIONS
1. Amyotrophic Lateral Sclerosis
8. Concussion,Brain /Spinal Injury
12.Inflammatory bowel conditions
13.Migrains (in human)
19. Post traumatic stress Disorder
Benefits of CBD In Pets
Works excellently on Epilepsy
Proper Sourcing of CBD
Just like you must take care in sourcing your own CBD products, you should make sure that the cannabis or hemp used in CBD products for your pets are grown in clean, organic, and environmentally responsible conditions. Several companies have been dinged by the FDA for selling CBD-products for pets with little or no actual CBD in them. A list of producers and their infractions is available on the FDA’s website, but reputable producers should be able to provide you with certified lab results for their products so you can verifythe CBD content. Anotherthings to consider when buying treats that have been baked or cooked is that CBD can be evaporated away entirely (the
boiling point of CBD is 320–356°F), so ask producers at what temperatures and for how long treats are baked or cooked. Sometimes CBD products will have essential oils added to the mix. Some essential oils have medicinal purposes, so make sure you research any essential oils added to understand why they might be there. Animals can be quite sensitive to essential oil additives, so if you purchase a product with essential oils, monitor your pet’s reaction. You should also checklabels to see if there are any chemical additives or preservatives in the product. And lastly, know your extraction methods, While CO2 extraction is generally considered the cleanest method, it is also the most expensive. Other methods, when done properly, can provide viable options. When in doubt, ask the producer about their extraction methods and to see their lab testing results.
Sources of CBD: Cannabis and Hemp
“The key difference between hemp plants and cannabis plants is resin content. Most hemp plants are low-resin plants. Cannabis plants are high-resin plants.” —Martin Lee, author and cofounder of Project CBD Did you know that CBD can come from both industrial hemp and cannabis? Both plants, though part of the same family, are genetically distinct entities with drasticallydifferent pasts and evolutionary paths. They both contain CBD but are markedly different plants in their cultivation, ability to produce CBD, and general application. There have been real and important legal gains for hemp farming in America in just the last decade or so, with industrial hemp farming resuming for the first time in 80 years. There is a lot of debate around hemp versus cannabis sources of CBD, and there is no clear right or wrong. Not only that, but the whole topic takes on a layer of complexity and confusion given the legal morass that hemp and cannabis currently wade around in. Because while people might think (and producers will often tell you) that hemp-derived CBD is legal, the reality is not so clear cut. In this new age of Cannabis sativa (referring to the larger taxonomic species that includes both plants) therapeutics, the genetic paths of hemp and cannabis are converging. We are cross-breeding and manipulating genes to offer a plethora of CBD-dominant products to patients, and the lines between hemp and cannabis are blurring. But for the moment, it’s still worth talking about these two sources of CBD as being distinctly different. Can we get controversial for a minute here? We have to when it comes to talking about hemp versus cannabis sources of CBD, because it is a HOT debate right now. Let’s begin with some key differences between the plants.
Hemp vs. Cannabis:
The Plants Both cannabis and hemp are members of the same species, Cannabis sativa, which is one of humanity’s oldest domesticated crops. Throughout history, we have grown different varieties of Cannabis sativa for different purposes. Over thousands of years of genetic selection for function, coupled with varying growing environments, two distinct plants have emerged that are very different in their cultivation and use. Tall, sturdy plants were grown by early civilizations to make a variety of clothing, rope, sails, and building materials. These plants were bred with other plants of similar characteristics, leading to the type of cannabis we now know as hemp. Today hemp plants are grown predominantly for their fiber while others are grown primarily for their seeds to produce oil. We use industrial hemp in a very large number of applications, from car parts to cooking oils, clothing to body creams. Meanwhile in different parts of the world, other Cannabis sativa plants became popular for medicinal and religious purposes, and eventually these plants were bred for their resinous trichomes (more on that later). This led to the unique varieties we now use for medicinal, spiritual, and recreational purposes. Today, medicinal cannabis plants consist of more euphoric THC-rich varieties, non-euphoric CBD-rich varieties, and points in between.
In different books, we refer to these plants as simply “cannabis.” What’s in a Name?
We refer to the plant you might know as “marijuana,” “weed,” or “pot” as simply “cannabis,” which is the proper name of the plant. We refrain from using the name “marijuana” because it is historically and racially charged. Hemp is a common and acceptable name for this distinct cousin of cannabis, and useful for distinguishing the two Cannabis sativa plants in discussion. Cannabis sativa, regardless of whether it is a fiber or seed plant (hemp) or a medicinal plant cannabis), all have the same structural features: stems, stalks, roots, flowers, and leaves. The basic anatomy of the cannabis plant. Hemp plant anatomy, while not exactly the same, is very similar.
Cannabis plants vary in height from 3 to 15 feet tall and have multiple branches with five to seven delicate serrated leaves spread like the fingers of an open hand. The plant’s leaves and flowers are covered, as is the entire plant, with tiny sticky hairs. These hairs, like the hairs on so many other plant species, are almost microscopic spikes that develop on the plant’s skin. The technical term for these plant hairs is trichomes, and it’s a term you will hear a lot in reference to cannabis because these trichomes are where almost all the good stuff is stored. Trichomes may resemble hair, but they’re not the same as our hair or the hair on your dog. Trichomes are living cells. They run the gamut in how they look and feel and get classified as either simple or glandular. Glandular trichomes, the ones found on cannabis and hemp, produce and store oils on the plant’s surface. All Cannabis sativa plants (hemp and cannabis) develop glandular trichomes. Just as mammal hair serves various protective purposes, including insulation and camouflage, so do trichomes. Trichomes provide a protective layer to the leaves and flowers from frost and UV rays. They also help reduce evaporation by protecting the plant from wind and heat. In many cases, trichomes protect plants from insects as well, with some structures so stiff or irritating (Stinging Nettle, for example) that they can keeps even large herbivores away. In these trichomes, there is an oily resin of biologically active phytochemicals produced by plants: flavonoids, terpenoids, phenolic compounds, and cannabinoids among others. Some phytochemicals (flavonoids) give plants their pretty colors, like the blue in blueberries and the red in raspberries; other phytochemicals (terpenes) give plants their distinctive aromas, like basil, sage, and rosemary. The phenolic compounds found in cannabis trichomes have antioxidant properties, an essential component of a healthy diet. There are lots of different phytochemicals in all the plant foods you eat, and some sources consider them to be nutrients. However, unlike vitamins and minerals, they’re not found to be essential nutrients, and there aren’t any established dietary reference intakes. Phytochemicals, like the active compounds in echinacea, for example, are extracted from plants, processed, and sold as dietary supplements. They’re generally considered to be safe, but there’s not much regulation regarding their dosages or even effectiveness.
Cannabinoids are the phytochemicals most people know of in cannabis:
THC, for example, and CBD. More specifically, they are referred to phytocannabinoids, meaning they come from plants, unlike the endogenous cannabinoids (anadamide and 2-AG) that our bodies naturally produce. As the plant grows and develops, the chemical composition of the trichomes changes dramatically. The “chemical cocktail” found within the trichomes of each strain has a different therapeutic effect that is unique to that strain, and even to that plant. There are many factors that contribute to the final chemical makeup of the plant: genetics, where it is grown (indoor, outdoor, greenhouse), what it is fed, when and how it is harvested, and how it is cured, to name but a few. Both cannabis and hemp plants develop these trichomes; however, because historically cannabis has been cultivated for medicinal and recreational use, it’s been bred to maximize the development of trichomes. This makes cannabis a much richer source of phytochemicals and cannabinoids. Industrial hemp plants are genetically predisposed to grow tall and lanky with small flowers, using much of its energy for developing fibers. Medicinal cannabis plants, on the other hand, are designed for phytochemical production, growing shorter and bushier, with more branches that support more flowers and therefore an abundance of therapeutic compounds. On cannabis, trichomes (and all the good phytochemicals that are stored in their resin) form in abundance on the flowers and upper leaves of female plants, and to a lesser extent on the lower leaves, branches, and stems. Male plants also develop trichomes but far less than the female plants, which is why cannabis growers focus on female plants almost exclusively. Another useful way to think about the hemp versus cannabis distinction, according to Martin Lee, is in resin content. Generally speaking, hemp plants are low in this phytochemical-rich oil, and cannabis plants are high-resin plants. As mentioned earlier, historically cannabis cultivation has focused on developing and maximizing trichome production, largely for THC content and the terpenes that give each varietal strain its particular character. Perhaps you’ve heard of some of the more famous strains like Maui Wowie, Lemon Haze, and Blue Dream. Today, with our improved understanding of CBD and all its therapeutic properties, many cannabis producers have begun to focus on CBD-rich plants. There are several cannabis plants whose primary cannabinoid is CBD, with very low levels of THC. In its cocktail of cannabinoids, there is proportionally more CBD in hemp than in cannabis: Hemp naturally produces a higher proportion of CBD as compared to other phytocannabinoids, like THC. You can think of it as a pie chart of phytocannabinoids, where in hemp’s pie chart, the CBD slice is bigger than in cannabis’s. This is one of the reasons that hemp has become such a popular source of CBD and has in turn led to an industrial hemp farming revival here in the US after decades of prohibition. That said, because hemp doesn’t naturally produce much in the way of trichomes (as compared to cannabis), it takes far more hemp to get an equivalent amount of CBD. In other words, the cannabis phytocannabinoid pie is just bigger than hemp’s. This presents a solid argument as to why CBD extraction might not be the best use of hemp, especially considering the myriad of other important uses we have discovered for hemp. Hemp is an extremely versatile plant. In fact, back in 1938, Popular Mechanics magazine touted hemp as “the new billion-dollar crop,” stating that it “can be used to produce more than 25,000 products, ranging from dynamite to Cellophane.”
Here are just a few of the most exciting applications for hemp:
■ Hempcrete (insulation for construction)
■ Clothing (antibacterial and odor fighting)
■ Energy storage as a superconductor
The CBD industry is a booming market, but it is still relatively young. The situation is complicated by prohibition, legal uncertainties,the absence of FDAregulations and insufficient consumer information. with time stronger regulations will help to improve the transparency and quality control behind these products. Low quality manufacturers will be pushed out of the market, and companies will learn how to increase their quality, decrease their prices, and still turn a profit, But until then patients and consumers must do their own product vetting.